Liquid chromatography-Mass Spectroscopy (LC-MS) is a technique which combines high performance liquid chromatography (HPLC) with mass spectroscopy. In this instrument ionization at atmospheric pressure is achieved by "electrospray ionization" (ESI) & "atmospheric pressure chemical ionization" (APCI) techniques. Both are soft ionization technique and compatible with most chromatographic separations.

Applications:
Quantitative analysis, impurity profiling, metabolite studies, pharmacokinetics, pharma and biomedical applications etc.

Specifications:

Mass Range:	20 - 4000 Da
Resolution:	0.2 Da
Ionisation method:	ESI, APCI
Analyser:	Single quadrupole
Detector:	Off-axis Dynolite photomultiplier
Vacuum system:	Split flow turbo-molecular source pump (160lts/sec) and two stage rotary backing pump
Computer:	Pentium 4 Processor based Compaq system and Windows NT OS
Software:	MassLynx 4.0
Solvents:	Methanol, Acetonitrile, Dichloromethane, water and chloroform
Unsuitable solvents:	Solvents like dimethyl formamide (DMF) and dimethyl sulfoxide (DMSO) cannot be used for high viscosity. Default system used here is 50:50 mixture of methanol and water with 0.1% acetic acid added for protonation.
Instructions to users:	Minimum of 500 µg of sample should be sent for analysis.

Contact Tel. No. : 0364 272 1814; 0364 272 1819 ; 0364 272 1810.